Abstract
THIS work was undertaken in an attempt to determine whether a difference could be demonstrated in the platelet counts of the blood of the rabbit right and left heart ventricles. That such a difference might occur suggested itself from the recent work of Sharnoff and Kim1,2, which studies revealed that megakaryocytes are present normally in the lung blood vessels of all mammals, where they appear to break up in the pulmonary capillary anastomoses into platelets. Therefore, it was postulated that if the lung vessels were a possible site of platelet formation, the blood of the left heart ventricle could contain a higher number of platelets than that of the right ventricle. The difference in number of platelets, it was believed, would depend only on the number of megakaryocytes present and breaking up at any one time in the lung vessels.
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References
Sharnoff, J. G., and Kim, E. S., Amer. Med. Assoc. Arch. Path., 66, 176 (1958).
Sharnoff, J. G., and Kim, E. S., Amer. Med. Assoc. Arch. Path., 66, 340 (1958).
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Sharnoff, J. G., Nature, 184, 75 (1959).
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SHARNOFF, J., SCARDINO, V. Platelet-Count Differences in Blood of the Rabbit Right and Left Heart Ventricles. Nature 187, 334–335 (1960). https://doi.org/10.1038/187334a0
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DOI: https://doi.org/10.1038/187334a0
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