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Production of Lysergic Acid Derivatives by a Strain of Claviceps paspali Stevens and Hall in Submerged Culture

Abstract

A STRAIN of Claviceps paspali Stevens and Hall isolated from the grass Paspalum distichum L. found growing on a hill in the neighbourhood of Rome was found, after propagation on a rye embryo grown on agar1, to be capable of producing lysergic acid derivatives in submerged culture.

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References

  1. Tonolo, A., Selected Sci. Papers from the Istituto Superiore di Sanitá, Rome, 2, 373 (1959).

  2. Voigt, R., Microchim. Acta, 619 (1959).

  3. Smith, S., and Timmis, G. M., J. Chem. Soc., 1440 (1936).

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ARCAMONE, F., BONINO, C., CHAIN, E. et al. Production of Lysergic Acid Derivatives by a Strain of Claviceps paspali Stevens and Hall in Submerged Culture. Nature 187, 238–239 (1960). https://doi.org/10.1038/187238a0

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  • DOI: https://doi.org/10.1038/187238a0

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