Letter | Published:

Treatment of Leishmania donovani Infections with Surface-active Agents

Naturevolume 187pages11291130 (1960) | Download Citation



‘TRITON W.R. 1339’, an arylalkyl polyoxyethylene ether of phenol, prepared by Rohm and Haas Co., Philadelphia, is a non-toxic surface-active agent, and was shown to exert a suppressive effect in experimental tuberculosis of mice1. ‘Macrocyclon’ is the polyoxyethylene ether containing on average 12.5 ethylene oxide units per chain, formed by reaction of ethylene oxide with a macrocyclic phenol and possesses similar antituberculous activity2.

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  1. 1

    Cornforth, J. W., Hart, P. D'A., Rees, R. J. W., and Stock, J. A., Nature, 168, 150 (1951).

  2. 2

    Cornforth, J. W., Hart, P. D'A., Nicholls, R. J., Rees, R. J. W., and Stock, J. A., Brit. J. Pharmacol. and Chemotherap., 10, 73 (1955).

  3. 3

    Fulton, J. D., Ann. Trop. Med. and Parasitol., 38, 147 (1944).

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  1. National Institute for Medical Research, Mill Hill, London, N.W.7

    • J. D. FULTON


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