Abstract
A CURIOUS feature of carcinogenesis in the skin of the mouse is the intense mast-cell reaction which gradually develops in the dermis immediately under the painted hyperplastic epidermis. Cramer and Simpson1 observed that some of these new mast cells exhibit a golden-brown fluorescence in ultraviolet light, providing that the frozen section has also been treated with formaldehyde.
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References
Cramer, W., and Simpson, W. L., Cancer Res., 4, 601 (1944).
Riley, J. F., and West, G. B., J. Physiol. (Lond.), 120, 528 (1953).
Benditt, E. P., Wong, R. L., Arase, M., and Roeper, E., Proc. Soc. Exp. Biol. (N.Y.), 90, 303 (1955).
Riley, J. F., Experientia, 13, 141 (1958).
Gomori, G., “Microscopic Histochemistry”, 128 (Univ. Chicago Press, 1952).
Pearse, A. G. E., “Histochemistry—Theoretical and Applied”, second edit., 925 (Churchill, 1960).
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COUPLAND, R., RILEY, J. Mast Cells and 5-Hydroxytryptamine in Precancerous Mouse Skin. Nature 187, 1128–1129 (1960). https://doi.org/10.1038/1871128a0
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DOI: https://doi.org/10.1038/1871128a0
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