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Influence of Different Types of Malnutrition on the 14C-Lysine Metabolism in Young Rats


IN the usual laboratory animals the typical corollaries of chronic shortage of proteins, fats, and carbohydrates have been thoroughly studied. Very little is known, however, of the changes in the intermediary metabolism. Since we were interested from a pædiatric point of view in the problems of malnutrition, we have investigated weanling Wistar rats (body-weight 35 ± 5 gm.). Five groups of ten animals each received for one week or more a synthetic diet (adapted from György) of the composition shown in Table 1.

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  1. 1

    Schreier, K., Zöller, E., Wissarianow, B. Vira, Nöller, H. G., and Madsen, P. O., Ärztl. Forsch., 10, 467 (1956).

  2. 2

    Allison, J. B., Ann. N.Y. Acad. Sci., 47, 245 (1946).

  3. 3

    Cox, W. M., Ellingson, R. C., and Mueller, A. J., Pediatrics, 11, 435 (1953).

  4. 4

    Munro, H. N., and Wikramanayake, W., J. Nutr., 52, 99 (1954). van Itallie, T. B., Waddell, W. R., Geyer, R. P., and Stare, F. J., Arch. Int. Med., 89, 353 (1952).

  5. 5

    Munro, H. N., and Thomsen, W. S. T., Metabolism, 2, 354 (1953).

  6. 6

    Schreier, K., Plückthun, H., and Hauss, H., Z. Kinderheilk., 73, 526 (1953/54).

  7. 7

    Albanese, A., Felch, W. C., Higgons, R. A., Vestal, B. L., and Stephanson, L., Metabolism, 20, 1 (1952).

  8. 8

    Davidova, and Novakovskaya, Biochimia (Russ.), 17, 570 (1952).

  9. 9

    Garrow, J. S., J. Clin. Invest., 38, 1241 (1959).

  10. 10

    Waterlow, J. C., Nature, 184, 1875 (1959).

  11. 11

    Solomon, G., and Tarver, H., J. Biol. Chem., 195, 447 (1952).

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