Letter | Published:

Diuretic Activity of 2-Amino-4-metachloro-anilino-1,3,5,triazine (R-37)



A SERIES of new derivatives of s-triazine synthesized in the Department of Chemotherapy, Haffkine Institute, Bombay, have been tested for their diuretic activity. Of the 12 compounds tested, 2-amino-4-meta-chloro-anilino-1,3,5,triazine (R-37), which is the metachloro analogue of amanozine, was found to be most promising. Diuretic activity was determined by a modified method of Lipschitz et al. (1943) developed in this laboratory1.

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  1. 1

    Mehta, D. J., Khazanie, R. G., and Sheth, U. K., Indian J. Physiol. Pharmacol., 3, 111 (1959).

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