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Mechanism of the Radiation Effect on the Synthesis of Deoxyribonucleic Acid

Abstract

WORK on the mechanism of the radiation effect upon the synthesis of deoxyribonucleic acid in human bone marrow cells in vitro indicated a biphasic X-ray dose-response curve1. To test the applicability of these findings to other mammalian cell systems, similar work has been carried out with mouse Ehrlich ascites tumour cells; this system also has the advantage of being a more homogeneous cell population than bone marrow.

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References

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BERRY, R., HELL, E., LAJTHA, L. et al. Mechanism of the Radiation Effect on the Synthesis of Deoxyribonucleic Acid. Nature 186, 563–564 (1960). https://doi.org/10.1038/186563a0

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