Abstract
THE secretion of aldosterone differs from that of other steroids of the adrenal cortex in that it is not directly under pituitary control. Current concepts favour a location in the diencephalon for the centre which controls aldosterone secretion1. The transmission of the stimulus from the centre to the effector gland cannot be nervous, since the isolated gland can respond to suitable provocations by an increased secretion of aldosterone2. It is therefore concluded that the stimulus is humoral.
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ROSS, E., McLEAN, E. & MILLER, G. Presence of Aldosterone-stimulating Hormone in Urine. Nature 185, 540 (1960). https://doi.org/10.1038/185540a0
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DOI: https://doi.org/10.1038/185540a0
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