Thiosulphate Metabolism in the Animal Organism

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THE occurrence of thiosulphate in animal urine was demonstrated by Schmiedeberg1 long ago, and Nyiri2 and Pirie3 showed that this substance is capable of being oxidized into sulphate by animal tissues. So far there has been a lack of more accurate details on the endogenic synthesis and the mechanism of oxidation of thiosulphate in the animal organism; but recently some light seems to have been thrown on the subject by the work of Sörbo.4

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  1. 1

    Schmiedeberg, O., Arch. Heilk., 8, 422 (1867).

  2. 2

    Nyiri, W., Biochem. Z., 141, 160 (1923).

  3. 3

    Pirie, N. W., Biochem. J., 28, 1063 (1924).

  4. 4

    Sörbo, B., Biochim. Biophys. Acta, 24, 324 (1957).

  5. 5

    Skarzvnski, B., Ostrowski, W., Krawczyk, A., Bull. de l'Acad. Polonaise Sci., C1. II, 5, 159 (1957). Ostrowski, W., Krawczyk, A., Acta Biochim. Polonica, 4, 249 (1957). Skarzynski, B., Ostrowski, W., Nature, 182, 933 (1958). Ostrowski, W., Skarzynski, B., Szczepkowski, T. W., Nukleonika, 3, 85 (1958). Skarzynski, B., Szczepkowski, T. W., Nature, 183, 1413 (1959).

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SKARZYNSKI, B., SZCZEPKOWSKI, T. & WEBER, M. Thiosulphate Metabolism in the Animal Organism. Nature 184, 994–995 (1959) doi:10.1038/184994a0

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