Thermoregulatory Heat Production in the Brain

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THE increase in the metabolic rate elicited in homoiothermal animals by exposure to cold is attributed by many investigators exclusively to striated muscle. According to others the liver and intestine have also to be considered as a source of extra heat, but only a few stress the importance of these viscera1,2. The participation of the brain in chemical thermoregulation has apparently not been investigated.

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  1. 1

    Fedorov, N. A., and Shur, E. I., Amer. J. Physiol., 137, 30 (1942).

  2. 2

    Donhoffer, Sz., Szegvári, Gy., Varga-Nagy, I., and Járai, I., Pflügers Arch. ges. Physiol., 265, 104 (1957).

  3. 3

    Donhoffer, Sz., Szegvári, Gy., Varga-Nagy, I., Járai, I., and Haug-László, Á., Acta physiol. Acad. Sci. Hung., 13, 37 (1957).

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DONHOFFER, S., SZEGVARI, G., JARAI, I. et al. Thermoregulatory Heat Production in the Brain. Nature 184, 993–994 (1959) doi:10.1038/184993a0

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