Hydrolysis of ‘Heated’ Hæmoglobin

Article metrics

Abstract

A DIMINISHED rate of alkaline denaturation of hæmoglobin is not confined to fœtal hæmoglobin only, as was already found by Singer et al. 1. Künzer2 in a survey on the occurrence of ‘fœtal’ hæmoglobin in various blood disorders found an alkali-resistant fraction in the anæmia developing after burns. Our observations have confirmed Künzer's and it has been found that this minor hæmoglobin abnormality develops during the first few hours after the burn and persists for some time. This abnormality develops before that of clinical anæmia and involves the patients' own and transfused cells. The detailed results of this work will be published elsewhere.

Access options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

References

  1. 1

    Singer, K., Chernoff, A. I., and Singer, L., Blood, 6, 413 (1951).

  2. 2

    Künzer, W., Z. Kinderh., 76, 58 (1954).

  3. 3

    Ingram, V. M., Biochim. Biophys. Acta, 28, 539 (1958).

  4. 4

    Meyer, H., Biochem. J., 67, 333 (1957).

  5. 5

    Löhr, G. W., Waller, H. D., Karges, O., Sehlegel, B., and Müller, A. A., Klin. Wschr., 36, 1008 (1958).

Download references

Author information

Rights and permissions

Reprints and Permissions

About this article

Cite this article

BAAR, S. Hydrolysis of ‘Heated’ Hæmoglobin. Nature 184, 986–987 (1959) doi:10.1038/184986b0

Download citation

Further reading

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.