Biosynthesis of Carotenes in Carrot Extracts

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Using methyl and carboxyl labelled acetate, Grob and Butler1,2 have shown that both carbon atoms of acetate are extensively incorporated into β-carotene synthesized by Mucor heimalis. They also found that pantothenic acid and pantetheine stimulate β-carotene synthesis; on the basis of this fact they have suggested that coenzyme A is involved in carotenogenesis. Studies have therefore been made to investigate the role of coenzyme A in the biogenesis of carotenoids; the present study details the results of the experiments on carotene biosynthesis using extracts prepared from carrots (Daucus carota).

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  1. 1

    Grob, E. C., and Butler, R., Helv. Chim. Acta, 8, 1313 (1955).

  2. 2

    Grob, E. C., and Butler, R., Helv. Chim. Acta, 7, 1908 (1955).

  3. 3

    Lepage, G. A., Biochem. Prep., 1, 5 (1949).

  4. 4

    Friend, J., Goodwin, T. W., and Griffiths, L. A., Biochem. J., 60, 649 (1955).

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MODI, V., PATWA, D. Biosynthesis of Carotenes in Carrot Extracts. Nature 184, 983–984 (1959) doi:10.1038/184983b0

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