Thiamine-sparing Action of Sorbitol in Rats and Mice

Article metrics

Abstract

DEFICIENCY of thiamine may be prevented in rats if they are given sorbitol. Administration of sorbitol to deficient rats cures the deficiency; withdrawal of the sorbitol leads to deficiency1. All these results have now been found also in mice (Fig. 1). Mice, like rats, also showed an enlarged cæcum when they were fed diets with sorbitol (Table 1).

Access options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

References

  1. 1

    Morgan, T. B., and Yudkin, J., Nature, 180, 543 (1957).

  2. 2

    Morgan, T. B., and Yudkin, J., Chem. and Indust., 37 (1959).

  3. 3

    Barnes, R. H., Fiala, G., McGehee, B., and Brown, A., J. Nut., 63, 489 (1957).

Download references

Author information

Rights and permissions

Reprints and Permissions

About this article

Cite this article

MORGAN, T., YUDKIN, J. Thiamine-sparing Action of Sorbitol in Rats and Mice. Nature 184, 909–910 (1959) doi:10.1038/184909a0

Download citation

Further reading

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.