Isolation of 2-Aminoethane Phosphonic Acid from Rumen Protozoa

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  • An Erratum to this article was published on 16 January 1960


IN the course of experiments on the amino-acid composition of rumen Protozoa, an unknown ninhydrin-positive substance was found by paper chromatography to be present in acid hydrolysates of the ether-ethanol soluble fraction of Protozoa. The substance was isolated in crystalline form and identified as 2-amino-ethane phosphonic acid, H2N·CH2·CH2·PO(OH)2, (synthesized by Finkelstein1, Kosolapoff2, Hackspill3 and Chavane4).

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  1. 1

    Finkelstein, J., J. Amer. Chem. Soc., 68, 2397 (1946).

  2. 2

    Kosolapoff, G. M., J. Amer. Chem. Soc., 69, 2112 (1947).

  3. 3

    Hackspill, M. L., C. R. Acad. Sci., Paris, 224, 406 (1947).

  4. 4

    Chavane, V., Ann. chim., 12, 4, 372 (1949).

  5. 5

    McNaught, M. L., Owen, E. C., Henry, K. M., and Kon, S. K., Biochem. J., 56, 151 (1954).

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HORIGUCHI, M., KANDATSTU, M. Isolation of 2-Aminoethane Phosphonic Acid from Rumen Protozoa. Nature 184, 901–902 (1959) doi:10.1038/184901b0

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