Differentiation Between a Growth-Promoting Factor and a Tumour-Susceptibility Factor in Eggs

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Abstract

SZEPSENWOL1 reported that feeding a diet composed mainly of cooked eggs to mice resulted in a significant increase in the number of animals spontaneously developing tumours. Denton2 found that feeding egg yolk increased the growth of chicks. Recently Hradec3 presented evidence, based on fractionation studies, which indicated the identity of the tumour susceptibility-enhancing and the growth-promoting factors. The study presented in this report was undertaken to determine by feeding experiment whether or not these factors were identical.

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References

  1. 1

    Szepsenwol, J., Proc. Soc. Exp. Biol. Med., 96, 332 (1957).

  2. 2

    Denton, C. A., Lillie, R. J., and Sizemore, J. R., Fed. Proc., 13, 455 (1954).

  3. 3

    Hradec, J., Nature, 182, 52 (1958).

  4. 4

    Hill, C. H., and Garren, H. W., Cancer Res., 16, 1019 (1956).

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HILL, C., GARREN, H. Differentiation Between a Growth-Promoting Factor and a Tumour-Susceptibility Factor in Eggs. Nature 184, 824–825 (1959) doi:10.1038/184824b0

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