Differential Analysis of the Effects of Phenothiazine-Tranquillizers on Emotional and Motor Behaviour in Experimental Animals

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Abstract

A RECENT communication1 pointed out that chlorpromazine simultaneously reduces emotional defæcation and ambulation in rats to the same degree. Ryall therefore concluded that the main behavioural effect of this drug in animal experiments is one of sedation and that the reduction in fear-motivated behaviour observed in animal experiments is secondary to the sedative action.

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TAESCHLER, M., CERLETTI, A. Differential Analysis of the Effects of Phenothiazine-Tranquillizers on Emotional and Motor Behaviour in Experimental Animals. Nature 184, 823–824 (1959) doi:10.1038/184823a0

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