Letter | Published:

Latent Period of X-Ray Induced Ageing: a Study Based on Mortality Rate and Tumour Incidence

Abstract

THE increase in age-specific chronic mortality rate that occurs after a single whole-body exposure to ionizing radiation has been commonly used as a parameter of ageing1. Whether or not the increase occurs immediately or only after a latent period is not known, owing to the fact that experiments are customarily initiated with young animals, for example, 50- to 125-day-old mice. The mortality rate is then so low that not even a large relative increase can be significantly established in groups of 50 animals.

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References

  1. 1

    Comfort, A., Radiation Res., Suppl. 1, 216 (1959).

  2. 2

    Kohn, H. I., Kallman, R. F., Berdjis, C. C., and DeOme, K. B., Radiation Res., 7, 407 (1957).

  3. 3

    Kohn, H. I., Radiation Res., Suppl. 1, 235 (1959).

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