Abstract
THE increase in age-specific chronic mortality rate that occurs after a single whole-body exposure to ionizing radiation has been commonly used as a parameter of ageing1. Whether or not the increase occurs immediately or only after a latent period is not known, owing to the fact that experiments are customarily initiated with young animals, for example, 50- to 125-day-old mice. The mortality rate is then so low that not even a large relative increase can be significantly established in groups of 50 animals.
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References
Comfort, A., Radiation Res., Suppl. 1, 216 (1959).
Kohn, H. I., Kallman, R. F., Berdjis, C. C., and DeOme, K. B., Radiation Res., 7, 407 (1957).
Kohn, H. I., Radiation Res., Suppl. 1, 235 (1959).
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KOHN, H., GUTTMAN, P. Latent Period of X-Ray Induced Ageing: a Study Based on Mortality Rate and Tumour Incidence. Nature 184, 735–736 (1959). https://doi.org/10.1038/184735a0
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DOI: https://doi.org/10.1038/184735a0
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