Letter | Published:

Accumulation of Dextran in Human Red Cells after Hæmolysis


MILD osmotic hæmolysis induces changes in the porosity of red cells, which seem to be largely reversible. It has been reported that ghosts can function as osmometers1 and that the kinetics of glycerol penetration may be unaltered by hæmolysis2. Hæmolysis has been used to introduce metabolically active substances into the ghosts3. The influx of ‘foreign’ hæmoglobin as a result of hæmolysis has also been reported4,5.

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