Letter | Published:

Accumulation of Dextran in Human Red Cells after Hæmolysis

Abstract

MILD osmotic hæmolysis induces changes in the porosity of red cells, which seem to be largely reversible. It has been reported that ghosts can function as osmometers1 and that the kinetics of glycerol penetration may be unaltered by hæmolysis2. Hæmolysis has been used to introduce metabolically active substances into the ghosts3. The influx of ‘foreign’ hæmoglobin as a result of hæmolysis has also been reported4,5.

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

References

  1. 1

    Teorell, T., J. Gen. Physiol., 35, 669 (1952).

  2. 2

    Stein, W. D., Exp. Cell Res., 11, 232 (1956).

  3. 3

    Gourley, D. R. H., J. App. Physiol., 10, 511 (1957).

  4. 4

    Betke, K., Klin. Wschr., 34, 101 (1956).

  5. 5

    Hoffman, J. F., J. Gen. Physiol., 42, 9 (1958).

  6. 6

    Marsden, N. V. B., and Zade-Oppen, M. (to be published).

  7. 7

    Marsden, N. V. B., Zade-Oppen, M., and Johansson, L. P., Exp. Cell Res., 13, 177 (1957).

  8. 8

    Wallenius, G., Acta Soc. Med. Upsal., Suppl. 4 (1954).

  9. 9

    Rothman, S., Adelson, E., Schwebel, A., and Langdell, R. D., Vox Sanguinis, 2, 104 (1957).

  10. 10

    Marsden, N. V. B., Exp. Cell. Res., 10, 755 (1956).

  11. 11

    Heedman, P. A., Exp. Cell Res., 14, 9 (1958).

Download references

Author information

Rights and permissions

Reprints and Permissions

About this article

Further reading

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.