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Sex Chromatin in Cultured Human Tissues

Abstract

THE sex chromatin clump of Barr has been reported as occurring in human female tissues cultured in vitro for short periods, and as not occurring in long-established cultures1,2. The purpose of this communication is to provide a quantitative summary of the available knowledge in this respect, and to indicate that sex chromatin apparently occurs routinely in suitably stained primary explants, but not in long cultured cells.

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References

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MILES, C. Sex Chromatin in Cultured Human Tissues. Nature 184, 477–478 (1959). https://doi.org/10.1038/184477a0

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