Letter | Published:

Organ Cultures of Total Mammary Glands of the Mouse


IN the course of experiments on hormonal influences upon tissue cultures of normal and malignant mammary tissue, a difficulty was encountered that in the common tissue culture and organ culture methods1 the duct systems are cut or disturbed by other means, resulting in wound-healing reactions of the epithelium. These reactions may interfere with the normal reactions of the epithelium to hormonal stimuli.

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  1. 1

    Lasfargues, E. Y., Exp. Cell Res., 13, 553 (1957): Anat. Rec., 127, 117 (1957). Elias, J. J., Science, 126, 842 (1957).

  2. 2

    Hardy, M. H., J. Anat., 84, 388 (1950).

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