Abstract
IN 1953 a gas in an aqueous solution, injected intravenously was used for the first time in studying the functioning of the lungs1. It was later shown that all acetylene so injected was eliminated rapidly through the lungs. About 40 per cent was eliminated in the first minute by a healthy person. If the concentration of acetylene in the expired air was registered continuously by means of a special infra-red spectro-photometric method a direct determination of the interval between the commencement of the injection and the initial appearance of acetylene in the expired air could be made. This is probably the most accurate method for measuring the time of circulation from the site of the injection to the lungs. The acetylene elimination capacity was specially low in the presence of extensive pulmonary fibrosis; elimination of the gas was also retarded during an asthmatic attack.
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References
Colldahl, H., Acta allergologica, Suppl. III, 61 (1953).
Colldahl, H., Third Europ. Congr. of allergy, Firenze 1956 (II Pensiero Scientifico, Roma).
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COLLDAHL, H., ALVÄGER, T. & UHLER, J. A New Method for Studying the Functioning of the Lungs. Nature 184, 372–373 (1959). https://doi.org/10.1038/184372a0
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DOI: https://doi.org/10.1038/184372a0
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