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Spectrophotofluorometric Assay of Griseofulvin

Nature volume 184, pages 364–365 (1959)Cite this article

Abstract

ALTHOUGH griseofulvin was isolated twenty years ago1 its value as a systemic anti-fungal agent was not appreciated until 1958, when Gentles2 reported that he had eradicated experimental ring-worm in guinea-pigs by its use in oral treatment. Clinical reports3–5 that have appeared since have evoked considerable interest among dermatologists and seem to have justified Gentles' optimism.

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References

  1. Oxford, A. E., Raistrick, H., and Simonart, P., Biochem. J., 33, 240 (1939).

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  2. Gentles, J. C., Nature, 182, 476 (1958).

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  3. Riehl, G., Meeting of the Austrian Dermatological Society, Vienna, (November 1958).

  4. Blank, H., and Roth, F. J., Meeting of the American Academy of Dermatology, Chicago (December 1958).

  5. Williams, D. I., Marten, R. H., and Sarkany, I., Lancet, ii, 1212 (1958).

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Authors and Affiliations

  1. Glaxo Laboratories Ltd., Greenford, Middlesex

    CAROLE BEDFORD, K. J. CHILD & E. G. TOMICH

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  1. CAROLE BEDFORD
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  2. K. J. CHILD
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  3. E. G. TOMICH
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BEDFORD, C., CHILD, K. & TOMICH, E. Spectrophotofluorometric Assay of Griseofulvin. Nature 184, 364–365 (1959). https://doi.org/10.1038/184364a0

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