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O-Phosphorylated and Unphosphorylated Peptide-Substrates suitable for Tryptic Action

Nature volume 184, pages 270–271 (1959)Cite this article

Abstract

A PREVIOUS communication reported the synthesis and action of trypsin on α-carbethoxy-L-lysyl-L-seryl-glycine and its O-phosphorylated analogue1. The striking resistance of the latter to the action of trypsin throws additional light on the unusual resistance of various phosphopeptides obtained from casein. It was, however, felt to be of interest to further investigate the inhibitory role of the O-phosphoric acid residue of serine along different lines.

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References

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Author notes

  1. D. THEODOROPOULOS: Swedish Medical Research Council Postdoctoral Fellow.

Authors and Affiliations

  1. Department of Medical Biochemistry, University of Gothenburg,

    D. THEODOROPOULOS, H. BENNICH & O. MELLANDER

Authors
  1. D. THEODOROPOULOS
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  2. H. BENNICH
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  3. O. MELLANDER
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THEODOROPOULOS, D., BENNICH, H. & MELLANDER, O. O-Phosphorylated and Unphosphorylated Peptide-Substrates suitable for Tryptic Action. Nature 184, 270–271 (1959). https://doi.org/10.1038/184270a0

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