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Rat Brain Glutathione and Pyridoxine Deficiency

Nature volume 184, pages 2028–2029 (1959)Cite this article

Abstract

DOUGLAS and Mortensen1 have shown that in vivo synthesis of glutathione from glycine occurs in rat brain. If this synthesis in brain is similar to that which is known to take place in liver then it would follow the general pattern described by Snoke and Bloch2. Lajtha, Berl and Waelsch3 have demonstrated that the systemic injection of glutamic acid labelled with carbon-14 is followed by a rapid incorporation of glutamate into the glutathione fraction of rat brain.

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Authors and Affiliations

  1. Medical Research Council Radiobiological Research Unit, Atomic Energy Research Establishment, Harwell, Berks

    M. J. ASHWOOD-SMITH & A. D. SMITH

Authors
  1. M. J. ASHWOOD-SMITH
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  2. A. D. SMITH
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ASHWOOD-SMITH, M., SMITH, A. Rat Brain Glutathione and Pyridoxine Deficiency. Nature 184, 2028–2029 (1959). https://doi.org/10.1038/1842028a0

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