Abstract
THE effect of staphylolysin on isolated organs has been hitherto studied mainly on isolated strips of rabbit or guinea pig gut1–5. The administration of the toxin causes a slow contraction, followed by unresponsiveness to the further application of toxins or drugs. It seemed to be of interest to perform experiments on the isolated uterus of the rat which does not respond to histamine.
Similar content being viewed by others
Article PDF
References
Feldberg, W., and Kellaway, C. H., Aust. J. Exp. Biol. Med. Sci., 16, 249 (1938).
Richmond, J. J., Reed, C. I., Shaughnessy, H. S., and Michael, V., J. Bact., 44, 201 (1942).
Anderson, K., James, D. M., and Marks, J., J. Hyg. (Camb.), 52, 492 (1954).
Dworetzky, M., Baldwin, H. S., and Smart, K. M., J. Allergy, 27, 39 (1956).
Brown, D. A., Prichard, B. N. C., and Quilliam, J. P., Brit. J. Pharm. Chem., 14, 59 (1959).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
WIEGERSHAUSEN, B. Some Pharmacological Effects of Staphylolysin on the Isolated Rat Uterus. Nature 184, 2017 (1959). https://doi.org/10.1038/1842017a0
Issue Date:
DOI: https://doi.org/10.1038/1842017a0
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.