Abstract
ALTHOUGH publications concerning measurement of vasopressin and oxytocin in blood and urine are legion, the lack of specificity of technique for concentration and bioassay of the trace amounts presumed to be present in biological fluids has led to wide variation in results and frank scepticism concerning their physiological significance1. Since bioassay techniques, although extremely sensitive, are inherently subject to wide error, a reliable quantitative method applicable to biological fluids demands a specific and sensitive technique for isolation and concentration of these polypeptides from blood or urine prior to bioassay.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
van Dyke, H. B., Adamsons, K., jun., and Engel, S. L., “Recent Prog. Hormone Res.”, 11, 1 (1955).
Bissett, G. W., and Lee, J., Lancet, 1, 1173 (1957).
Heller, H., and Lederis, K., Nature, 182, 1231 (1958).
Dieckert, J. W., Carney, W. B., Ory, R. L., and Morris, N. J., Anal. Chem., 30, 1442 (1958).
Dickert, S. E., J. Physiol., 122, 149 (1953).
Gaddum, J. H., Brit. J. Pharm. and Chemother., 8, 321 (1953).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
ARIMURA, A., DINGMAN, J. Specific and Sensitive Assay Method for Vasopressin and Oxytocin using Glass-Paper Chromatography. Nature 184, 1874–1875 (1959). https://doi.org/10.1038/1841874a0
Issue Date:
DOI: https://doi.org/10.1038/1841874a0
This article is cited by
-
Untersuchungen zur Spezifität des Adiuretin-Nachweises an der alkoholnarkotisierten, hydratisierten Ratte mit einer modifizierten Registriertechnik
Zeitschrift für Die Gesamte Experimentelle Medizin (1965)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.