Letter | Published:

Electron Microscopy of Autoradiographed Radioactive Particles


THE combination of the techniques of electron microscopy and autoradiography was first described by Liquier-Milward1. O'Brien and one of us (L.A.G.) later described the application of a similar technique to ultra-thin sections of yeast2. This communication describes a further modification of the technique for the identification of radioactive particles collected on millipore filters. This work was in support of an investigation into the effects of the inhalation of radioactive particles.

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  1. 1

    Liquier-Milward, J., Nature, 177, 619 (1956).

  2. 2

    O'Brien, R. T., and George, L. A., II, Nature, 183, 1461 (1959).

  3. 3

    Kalmus, E. H., J. App. Phys., 25, 87 (1954).

  4. 4

    Mastel, B. (personal communication).

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