Abstract
ITO et al. 1 and Lindenbaum2 injected the sodium or potassium salt of rhodizonic acid in order to increase the excretion of strontium-90 in rats. The former observed a slowing, the latter an acceleration in the elimination of strontium-90. We found that sodium rhodizonate given parenterally slows the removal of strontium-90 from the body, mainly by depressing the urinary excretion of radiostrontium. The effect was dependent upon the amount of rhodizonate injected (Fig. 1).
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Ito, J., Tsurufuji, S., Ishidate, M., Tamure, Z., and Takite, H., J. Pharm. Soc. Japan, 76, 1406 (1956).
Lindenbaum, A., ANL, 5732, 134 (1957).
Cohn, S. H., and Gong, J. K., Proc. Soc. Exp. Biol. Med., 83, 550 (1953).
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MacDonald, N. S., Spair, P. C., Ezmirlian, F., and Rounds, D. E., J. Nutrit., 57, 555 (1957).
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VOLF, V. Attempts to Modify the Normal Metabolism of Strontium-90 in Rats. Nature 184, 1401 (1959). https://doi.org/10.1038/1841401a0
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DOI: https://doi.org/10.1038/1841401a0
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