Abstract
THE active transport of sodium is an important function of the amphibian skin; this transport can be increased by extracts of mammalian neurohypophysis1. In Rana esculenta, oxytocin alone is active, vaso-pressin having only a small effect corresponding to its intrinsic oxytocic activity. On the other hand, neuro-hypophyseal extracts of Amphibia and fish influence this transport at such low concentrations, that it would seem reasonable to postulate that their action is due to an unknown principle, more specific to sodium transport than is oxytocin itself2,3.
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References
Ussing, H. H., Eighth Symposium of the Society for Experimental Biology (Cambridge University Press, 1954).
Morel, F., Maetz, J., and Lucarain, Cl., Biochim. Biophys. Acta, 28, 619 (1958).
Maetz, J., Morel F., and Race, B., Biochim. Biophys. Acta (in the press).
Holton, P., Brit. J. Pharmacol., 3, 328 (1948).
Morel, F., and Maetz, J., J. Physiologie, 51, 536 (1959).
Maetz, J., Jard, S., and Morel, F., C.R. Acad. Sci., 247, 516 (1958).
Baldwin, E., “An Introduction to Comparative Biochemistry (Cambridge University Press, 1948).
Heller, H., Experientia, 6, 368 (1950).
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MAETZ, J., MOREL, F. & LAHLOUH, B. Natriferin: A New Hormonal Principle in the Neurohypophysis of Certain Vertebrates. Nature 184, 1236–1237 (1959). https://doi.org/10.1038/1841236b0
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DOI: https://doi.org/10.1038/1841236b0
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