Abstract
HÆMATOLOGICAL use of Schiff's reagent for the Feulgen reaction1 has been described by Gardikas and Israels2. This technique, or minor variations of it, has been used extensively to identify the number of nucleoli in primitive normal or pathological leucocytes. There is a perinucleolar concentration of nuclear protein, but the nucleoli themselves are free of deoxyribonucleic acid.
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References
Feulgen, R., and Rossenbeck, Z., Z. physiol. Chem., 135, 203 (1924).
Gardikas, C., and Israels, M. C. G., J. Clin. Path., 1, 226 (1948).
Pearse, A. G. E., J. Clin. Path., 4, 1 (1951).
Pearse, A. G. E., “Histochemistry” (Churchill, London, 1953).
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ARCHER, R. Feulgen–Naphthoic Acid Hydrazide Reaction applied to Blood Smears. Nature 183, 820 (1959). https://doi.org/10.1038/183820a0
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DOI: https://doi.org/10.1038/183820a0
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