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Reduced Activity of Histaminase in Rats sensitized by Bordetella pertussis

Nature volume 183, pages 755–756 (1959)Cite this article

Abstract

SINCE Parfentjev and Goodline1 published their work on histamine hypersensitivity induced by inoculation of Bordetella pertussis (reviewed by Kind2) a number of papers on the subject have appeared; but little has been reported of the related biochemical changes in connexion with susceptibility to histamine. Inactivation of histamine by lung tissues from mice inoculated with B. pertussis was reported by Kind et al. 3 to decrease as compared with tissues from uninoculated mice. But this interesting result was not repeated by the same authors. More recently, Fishel4 has examined changes in amino-acids, histamine and glutathione contents in various organs from inoculated mice, revealing no specific changes referable to histamine hypersensitivity. The present communication deals with the results concerning reduced activities of histaminase in tissue of rats inoculated with B. pertussis.

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References

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Authors
  1. MAKOTO NIWA
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  2. YUTAKA YAMADEYA
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  3. TOSHITAKA MATSUI
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  4. YOSHIO KUWAJIMA
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NIWA, M., YAMADEYA, Y., MATSUI, T. et al. Reduced Activity of Histaminase in Rats sensitized by Bordetella pertussis . Nature 183, 755–756 (1959). https://doi.org/10.1038/183755a0

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  • DOI: https://doi.org/10.1038/183755a0

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