Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Antigenic Stimulus of Exsheathing Fluid in Self-Cure of Sheep infested with Haemonchus contortus

Abstract

IT has been reported that the second ecdysis of Ascaris lumbricoides is probably important in the stimulation of protective immunity in guinea pigs1–2. Up to 4 days after the administration of ova, developing larvæ appear to be of little importance in stimulating immunity and are themselves unaffected by immune processes. Using the Forssman antibody as a natural marker, it was demonstrated that a large release of antibody does not occur until 4–5 days after the administration of ova3. This period coincides with the second ecdysis, and it was suggested that this process is important in stimulating immunity by the liberation of antigens.

This is a preview of subscription content, access via your institution

Access options

Rent or buy this article

Prices vary by article type

from$1.95

to$39.95

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Soulsby, E. J. L., Nature, 179, 783 (1957).

    Article  ADS  CAS  Google Scholar 

  2. Soulsby, E. J. L., Vet. Rev. Annot., 4, 1 (1958).

    Google Scholar 

  3. Soulsby, E. J. L., J. Comp. Path. Ther., 68, 71 (1958).

    Article  CAS  Google Scholar 

  4. Sommerville, R. I., Exp. Parasit., 6, 18 (1957).

    Article  CAS  Google Scholar 

  5. Rogers, W. P., and Sommerville, R. I., Nature, 179, 619 (1957).

    Article  ADS  CAS  Google Scholar 

  6. Stewart, D. F., Aust. J. Agric. Res., 4, 100 (1953).

    Article  Google Scholar 

  7. Stewart, D. F., Aust. J. Agric. Res., 1, 285 (1950).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

SOULSBY, E., SOMMERVILLE, R. & STEWART, D. Antigenic Stimulus of Exsheathing Fluid in Self-Cure of Sheep infested with Haemonchus contortus . Nature 183, 553–554 (1959). https://doi.org/10.1038/183553b0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/183553b0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing