Abstract
IT has been reported that the second ecdysis of Ascaris lumbricoides is probably important in the stimulation of protective immunity in guinea pigs1–2. Up to 4 days after the administration of ova, developing larvæ appear to be of little importance in stimulating immunity and are themselves unaffected by immune processes. Using the Forssman antibody as a natural marker, it was demonstrated that a large release of antibody does not occur until 4–5 days after the administration of ova3. This period coincides with the second ecdysis, and it was suggested that this process is important in stimulating immunity by the liberation of antigens.
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References
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SOULSBY, E., SOMMERVILLE, R. & STEWART, D. Antigenic Stimulus of Exsheathing Fluid in Self-Cure of Sheep infested with Haemonchus contortus . Nature 183, 553–554 (1959). https://doi.org/10.1038/183553b0
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DOI: https://doi.org/10.1038/183553b0
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