Abstract
IN a previous communication1, we described the isolation of progesterone from the adrenal venous blood of cattle. During the course of this work it was observed that progesterone was sometimes accompanied by a more polar α,β-unsaturated ketosteroid in the young calf. Since changes in the nature of adrenocortical secretion have been observed during the early life of calves2, it seemed appropriate to examine, first, the possibility of a relationship between progesterone and corticoid secretion; secondly, the relationship between the unknown steroid and progesterone; and thirdly, the chemical nature of the unknown steroid.
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References
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BALFOUR, W., COMLINE, R. & SHORT, R. Changes in the Secretion of 20α-Hydroxypregn-4-en-3-one by the Adrenal Gland of Young Calves. Nature 183, 467–468 (1959). https://doi.org/10.1038/183467a0
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DOI: https://doi.org/10.1038/183467a0
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