Abstract
THE addition of vanadium to liver sections of normal animals can prevent the synthesis of cholesterol from both mevalonic acid and acetate1. Diets containing vanadyl sulphate do not, however, alter the cholesterol-levels in the serum or liver after being administered for six weeks to rabbits fed on high-cholesterol diets, though they considerably reduce the cholesterol concentration in the aorta and appreciably lower the capacity of the liver to synthesize cholesterol1,2.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Rent or buy this article
Prices vary by article type
from$1.95
to$39.95
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Curran, G. L., J. Biol. Chem., 210, 765 (1954). Curran, G. L., and Costello, R. L., J. Exp. Med., 103, 49 (1956). Azarnoff, D. L., and Curran, G. L., J. Amer. Chem. Soc., 79, 2969 (1957).
Mountain, J. T., Stockwell, F. R., and Stokinger, H. E., Proc. Soc. Exp. Biol. Med., 92, 582 (1956).
Frantz, I. O., and Hinkelmann, B. T., J. Exp. Med., 101, 225 (1955).
Sperry, W. M., and Webb, M., J. Biol. Chem., 187, 97 (1950).
Abell, L. L., Levy, B. B., Brodie, B. B., and Kendall, F. E., J. Biol. Chem., 195, 357 (1952).
Kaplan, N. O., and Lipmann, F., J. Biol. Chem., 173, 37 (1948).
Lowry, O. H., Rosebrough, N. Y., Farr, A. L., and Randall, R. J., J. Biol. Chem., 193, 265 (1951).
Mountain, J. T., Delker, L. L., and Stokinger, H. E., A.M.A. Arch. Indust. Hyg., 8, 406 (1953). Snyder, F., and Cornatzer, W. E., Nature, 182, 462 (1958).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
MASCITELLI-CORIANDOLI, E., CITTERIO, C. Effects of Vanadium upon Liver Coenzyme A in Rats. Nature 183, 1527–1528 (1959). https://doi.org/10.1038/1831527a0
Issue Date:
DOI: https://doi.org/10.1038/1831527a0
This article is cited by
-
New investigations on acute toxicities of vanadium oxides
Monatshefte f�r Chemie - Chemical Monthly (1994)
-
In vitro biosynthesis of β-carotene by bovine corpus luteum tissue
Lipids (1969)
-
Influence of vanadyl sulfate on hypercholesterinemia following a single injection of cholesterol
Bulletin of Experimental Biology and Medicine (1966)
-
Acetylcholine metabolism in the brain of rats treated with vanadyl sulfate and certain phenylacetic acid derivatives
Bulletin of Experimental Biology and Medicine (1964)
-
Intracellular Distribution of Ubiquinone in Rat Liver under Certain Stress Conditions
Nature (1961)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
