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Effects of Vanadium upon Liver Coenzyme A in Rats


THE addition of vanadium to liver sections of normal animals can prevent the synthesis of cholesterol from both mevalonic acid and acetate1. Diets containing vanadyl sulphate do not, however, alter the cholesterol-levels in the serum or liver after being administered for six weeks to rabbits fed on high-cholesterol diets, though they considerably reduce the cholesterol concentration in the aorta and appreciably lower the capacity of the liver to synthesize cholesterol1,2.

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MASCITELLI-CORIANDOLI, E., CITTERIO, C. Effects of Vanadium upon Liver Coenzyme A in Rats. Nature 183, 1527–1528 (1959).

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