Abstract
IT has been shown that the cardiac glycosides inhibit the transport of cations in human red cells1–3, and it appears that this effect is exerted directly on the transport mechanism rather than on its energy supply3–5. Though some studies of the effect of these drugs on transport of sodium have been made, interest has been centred on the inhibition of transport of potassium. The present communication is concerned with the relationship between the sodium and potassium fluxes in human red cells treated with the cardiac glycoside, ouabain.
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References
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GILL, T., SOLOMON, A. Effect of Ouabain on Sodium Flux in Human Red Cells. Nature 183, 1127–1128 (1959). https://doi.org/10.1038/1831127a0
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DOI: https://doi.org/10.1038/1831127a0
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