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Changes produced in Serum Lipoproteins of Dogs by Cellulose containing Methyl Groups

Abstract

IT has been observed by several authors that macromolecular polysaccharides, especially those containing sulphate groups, cause significant alterations in the lipoprotein patterns of sera1,2. In the course of previous studies on the effect of methyl-cellulose on blood-proteins3 certain changes in serum lipids were also noted. So it seemed to be of interest to examine what influence methylcellulose of high molecular weight (82,000) exerts in vitro as well as in vivo on the lipoproteins of sera of experimental animals.

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References

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  2. Hawkins, W. W., and Leonard, V. G., Canad. J. Biochem. Physiol., 36, 161 (1958). Brown, W. D., Quart. J. Exp. Physiol., 37, 215 (1952).

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FRÖHLICH, M., BALÁZS, V., KOVÁCS, K. et al. Changes produced in Serum Lipoproteins of Dogs by Cellulose containing Methyl Groups. Nature 183, 1119–1120 (1959). https://doi.org/10.1038/1831119a0

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