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‘Pheromones’: a New Term for a Class of Biologically Active Substances


DURING the past few decades, investigations have been made into various active substances which, though they resemble hormones in some respects, cannot be included among them. For example, the sexual attractants of butterflies are, like hormones, produced and secreted by special glands; minute amounts cause a specific reaction in the receptor organ (the antenna of the male), which eventually leads to a state of copulative readiness. Unlike hormones, however, the substance is not secreted into the blood but outside the body; it does not serve humoral correlation within the organism but communication between individuals.

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  1. Bethe, A., Naturwiss., 20, 177 (1932).

    Article  ADS  CAS  Google Scholar 

  2. Karlson, P., and Butenandt, A., Ann. Rev. Ent., 4 (in the press).

  3. Butler, C. G., Proc. Roy. Soc., B, 147, 275 (1957).

    Article  ADS  Google Scholar 

  4. Stumper, R., Mitt. schweiz. ent. Ges., 19, 373 (1956).

    Google Scholar 

  5. Lüscher, M., Insectes Sociaux, 3, 119 (1956); Rev. suisse Zool., 63, 261 (1956).

    Article  Google Scholar 

  6. Götz, B., Experientia, 7, 408 (1951).

    Article  Google Scholar 

  7. Butenandt, A., Nova Acta Leop. Carol., N.F., 17, 445 (1955).

    CAS  Google Scholar 

  8. Wharton, D. R. A., Miller, G. L., and Wharton, M. L., J. Gen. Physiol., 37, 461 (1954).

    Article  CAS  Google Scholar 

  9. Renner, M., Z. vergl. Physiol. (in the press).

  10. Kullenberg, B., Zool. Bidr. Uppsala, 31, 253 (1956).

    Google Scholar 

  11. Forster, G. R., J. Mar. Biol. Assoc. U.K., 30, 333 (1951).

    Article  Google Scholar 

  12. Frisch, K. v., Z. vergl. Physiol., 29, 46 (1941).

    Article  Google Scholar 

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KARLSON, P., LÜSCHER, M. ‘Pheromones’: a New Term for a Class of Biologically Active Substances. Nature 183, 55–56 (1959).

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