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Reduction of Neotetrazolium Chloride by Vitamin K3

Abstract

MENADIONE (vitamin K3, 2-methyl-1.4-naphthaquinone) has become increasingly associated with pathways of electron transfer. It has been implicated in the nitrate reductase sequence; in the processes of photosynthetic phosphorylation; in a non-phosphorylative oxidative pathway; in menadione reductase and in the general respiratory chain and associated processes of oxidative phosphorylation (ef. ref. 1). Menadione has recently been associated with an enzyme sequence connecting the oxidation of succinate with the reduction of neotetrazolium chloride1. The vitamin K3 involved in such reactions can be followed by spectrophotometric rate measurements2.

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References

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SLATER, T. Reduction of Neotetrazolium Chloride by Vitamin K3 . Nature 183, 50–51 (1959). https://doi.org/10.1038/183050a0

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