Abstract
A METHOD of testing the potentialities of nuclei from embryonic cells has been described by Briggs and King1. The method consists of transferring a nucleus from an embryonic cell into an enucleated and unfertilized egg of the same species. King and Briggs2, who have performed their experiments on Rana pipiens, found that normal tadpoles resulted from eggs with transplanted nuclei in about 35 per cent of cases in which the nuclei were taken from blastulæ, but in only about 6 per cent of cases in which the nuclei were taken from late gastrula endoderm; they have not reported normal development from nuclei of post-neurulæ or later stages.
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References
Briggs, R., and King, T. J., J. Exp. Zool., 122, 485 (1953).
King, T. J., and Briggs, R., Cold Spring Harbor Symp., 21, 271 (1956).
Elsdale, T. R., Fischberg, M., and Smith, S., Exp. Cell Res. (in the press).
Nieuwkoop, P. D., and Faber, J., “Normal Table of Xenopus laevis” (1956).
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GURDON, J., ELSDALE, T. & FISCHBERG, M. Sexually Mature Individuals of Xenopus laevis from the Transplantation of Single Somatic Nuclei. Nature 182, 64–65 (1958). https://doi.org/10.1038/182064a0
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DOI: https://doi.org/10.1038/182064a0
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