Letter | Published:

A Lipopolysaccharide Antigen of the Treponema

Abstract

IMMUNOCHEMICAL studies carried out by D'Alessandro et al. 1 on a non-pathogenic, culturable treponeme, the so-called Reiter treponeme, revealed the presence of four antigenic components: (1) a thermolabile protein; (2) a specific, thermostable antigen with polysaccharide characteristics; (3) a lipoid, corresponding to the ubiquitous lipidic antigen cardiolipin; (4) another lipoid similar to the organ-specific cerebral antigen of Witebsky2. These studies led to the conclusion that the treponemes, like other organisms, are mosaics of antigens, and a safe basis was established for a better understanding of the complex serological response of the infected host.

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

References

  1. 1

    D'Alessandro, G., Oddo, F. G., Comes, R., and Dardanoni, L., Riv. Ist. Sierot. Ital., 24, 134 (1949).

  2. 2

    Witebsky, E., Münch. med. Wochenschr., 1914 (1927).

  3. 3

    Dardanoni, L., and Censuales, S., Riv. Ist. Sierot. Ital., 32, 483 (1957).

  4. 4

    Portnoy, J., and Magnuson, H., J. Immunol., 75, 348 (1955).

Download references

Author information

Rights and permissions

Reprints and Permissions

About this article

Further reading

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.