Letter | Published:

Chromosome Breakage in Vicia faba by Ozone


IMPORTANT to an understanding of the biological effects of high-energy radiations is the concept of active radical formation in water1. The inability of hydrogen peroxide per se to simulate irradiation effects at concentrations expected in the cytoplasm of irradiated cells2 has focused attention on the active radicals OH and HO2. The chemical activity of such free radicals produced by the catalytic decomposition of hydrogen peroxide with ferric ions has recently been discussed3, and Phillips4 describes the production of chromosome aberrations in barley by these hydrogen peroxide ‘precursors’.

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.


All prices are NET prices.


  1. 1

    Weiss, J., Nature, 157, 584 (1946). Gray, L. H., Brit. J. Radiol., 25, 235 (1952).

  2. 2

    Barron, A. S. G., et al., Arch. Biochem. Biophys., 41, 188 (1952). Kimball, R. F., and Gaither, N., Proc. Soc. Exp. Biol. Med., 80, 525 (1952).

  3. 3

    Scholes, G., and Weiss, J., Exp. Cell Res., Supp. 2 (1952).

  4. 4

    Phillips, L. L., Science, 125, 889 (1956).

  5. 5

    Weiss, J., Trans. Farad. Soc., 31, 668 (1935). Moelwyn-Hughes, E. A., “Kinetics of Reactions in Solution” (Oxf. Univ. Press, 1947).

  6. 6

    Alder, M. C., and Hill, R. H., J. Amer. Chem. Soc., 72, 1884 (1950).

  7. 7

    Stumm, W., Helv. Chim. Acta, 37, 773 (1954).

  8. 8

    Wolff, S., Genetics, 39, 356 (1954).

Download references

Author information

Rights and permissions

Reprints and Permissions

About this article

Further reading


By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.