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Growth and Titration of Louping-ill Virus in Monolayer Tissue Culture of Pig Kidney


Rivers and Ward1 reported the propagation of louping-ill virus in a Maitland-type culture of chick embryo tissue. More recently, Oker-Blom2 has described a cytopathogenicity in HeLa cell culture induced by louping-ill which permitted titration of the virus. I have found a specific cytopathogenic effect by the same viral agent in monolayer culture of pig kidney.

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  1. 1

    Rivers, T. M., and Ward, S. M., Proc. Soc. Exp. Biol. Med., 30, 1300 (1932–33).

  2. 2

    Oker-Blom, N., Ann. Med. Exp. Fenn., 34, 199 (1956).

  3. 3

    Reed, L. J., and Muench, H., Amer. J. Hyg., 27, 493 (1938).

  4. 4

    Rappaport, C., Bull. World Health Org., 14, 147 (1956).

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