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Soluble Antigens in Microsomes and Other Cell-Fractions of Rat Liver


IT has been known for some time that particulate material sedimentable by high speed from tissue cells has characteristic immunological properties, and the antigenic specificity of isolated cell fractions has been studied in a variety of normal and tumour tissues1. These investigations not unexpectedly revealed a high degree of antigenic complexity of the different cell fractions, making further analysis difficult by the methods at hand. However, the results seemed encouraging enough to warrant an extension of the immunological work to the various soluble antigens characterizing different parts of the cell. An investigation of this sort has been carried out in our laboratory, and a detailed report of it will be published later.

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