Letter | Published:

Enzyme Changes in the Ageing Periosteum


ACID and alkaline phosphatase, cytochrome oxidase and succinic dehydrogenase activities of the periosteum of the femora of 100 normal and 100 traumatized animals were studied histochemically. The animals ranged from newborn to more than one year of age. Trauma was induced by drilling a hole in the midfemoral region.

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.


All prices are NET prices.


  1. 1

    Zorzoli, A., J. Geront., 10, 156 (1955).

  2. 2

    Weinbach, E. C., and Garbus, J., Nature, 178, 1225 (1956).

  3. 3

    Bourne, G. H., Nature, 179, 472 (1957).

  4. 4

    Bourne, G. H., Proc. European Conf. Gerontology, Experientia, Supp. IV, 61 (Birkhauser, Basel, 1957).

Download references

Author information

Rights and permissions

Reprints and Permissions

About this article

Further reading


By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.