A Case of Limitation of Phenotypic Variation


JINKS1 suggests that where phenotypic variation is caused by a cytoplasmic system, the range of phenotypic expression attainable by the system would have quite definite limits imposed by the system itself (cytoplasmic limits) or, by the non-viability of phenotypes lying outside these limits (physiological limits). Cytoplasmic limits would result where further changes in cytoplasmic content are impossible, as when all cytoplasmic elements involved in the change are lost. Physiological limits would result where although more extreme changes in the cytoplasm are possible they would lead only to non-viable phenotypes. Jinks's results suggested a physiological basis to limits of variation obtained in Aspergillus glaucus.

Access options

Rent or Buy article

Get time limited or full article access on ReadCube.


All prices are NET prices.


  1. 1

    Jinks, J. L., Proc. Roy. Soc., B, 146, 527 (1957).

Download references

Author information

Rights and permissions

Reprints and Permissions

About this article

Cite this article

FITZGERALD, P. A Case of Limitation of Phenotypic Variation. Nature 181, 436 (1958). https://doi.org/10.1038/181436a0

Download citation

Further reading


By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.