Nuclear Transplantation in Xenopus laevis

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Briggs and King1 have devised a technique with which they were able to transplant nuclei from cells of early embryos into unfertilized eggs of Rana pipiens from which the female pronucleus had been removed. In this way they could test the extent to which a nucleus from embryos up to neurula stages could produce normal development when transplanted into an enucleated egg2.

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  1. 1

    Briggs, R., and King, T. J., J. Exp. Zool., 122, 485 (1953).

  2. 2

    King, T. J., and Briggs, R., Proc. Nat. Acad. Sci., 41, 321 (1955).

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FISCHBERG, M., GURDON, J. & ELSDALE, T. Nuclear Transplantation in Xenopus laevis . Nature 181, 424 (1958) doi:10.1038/181424a0

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