Adrenaline and Noradrenaline Content of the Adrenal Gland of the Rat following Depletion with Reserpine

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Abstract

IT has been shown that reserpine causes a loss of catechol amines from cat1 and rabbit2 adrenal glands. In the experiments reported here a study has been made of the adrenaline and noradrenaline content of rat adrenal glands over a period of a month, reserpine being administered for the first 3 days. Thus information concerning the loss and replacement of amines was obtained.

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References

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    Holzbauer, M., and Vogt, M., J. Neurochem., 1, 8 (1956).

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    Carlsson, A., and Hillarp, N.-Å, Kungl. fysiogr. Sällsk. Lund Förh., 26, Nr. 8 (1956).

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    Bülbring, E., Brit. J. Pharmacol., 4, 234 (1949).

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    Butterworth, K. R., and Mann, M., Brit. J. Pharmacol., 12, 415 (1957).

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CALLINGHAM, B., MANN, M. Adrenaline and Noradrenaline Content of the Adrenal Gland of the Rat following Depletion with Reserpine. Nature 181, 423–424 (1958) doi:10.1038/181423a0

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