Isomeric Chondroitin Sulphates

Article metrics

Abstract

A RECENT communication1 claims to “confirm Meyer's hypothesis that chondroitin sulphates A and C are only two fractions of the same polydisperse substance”. Apparent lack of agreement in nomenclature2–4 further emphasizes the need for clear differentiation of the isomeric chondroitin sulphates of connective tissue. These three substances, chondroitin sulphate A, chondroitin sulphate B and chondroitin sulphate C, respectively, in the nomenclature of Meyer et al. 2, have been found to be linear polyelectrolytes with similar chain configuration-charge relationships. Chondroitin sulphates A and C have been clearly distinguished as molecular individuals by comparison of molecular constants and physical properties.

Access options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

References

  1. 1

    Bernardi, G., Happey, F., and Naylor, A., Nature, 180, 1341 (1957).

  2. 2

    Meyer, K., Davidson, E., Linker, A., and Hoffman, P., Biochim. Biophys. Acta, 21, 506 (1956).

  3. 3

    Orr, S. F. D., Biochim. Biophys. Acta, 14, 173 (1954).

  4. 4

    Hall, D. A., Lloyd, P. F., Happey, F., Horton, W. G., and Naylor, A., Nature, 179, 1078 (1957).

  5. 5

    Mathews, M. B., and Dorfman, A., Arch. Biochem. Biophys., 42, 41 (1953).

  6. 6

    Marbet, R., and Winterstein, A., Helv. Chim. Acta, 34, 2311 (1951).

  7. 7

    Naganishi, K., Takahashi, N., and Egami, F., Bull. Chem. Soc. Japan, 29, 434 (1956).

  8. 8

    Schiller, S., Mathews, M. B., Jefferson, H., Ludowieg, J., and Dorfman, A., J. Biol. Chem., 211, 717 (1954).

  9. 9

    Jeanloz, R. W., Stoffyn, P. J., and Tremege, M., Federation Proc., 16, 201 (1957). Cifonelli, J. A., Ludowieg, J., and Dorfman, A., Fed. Proc., 16, 165 (1957).

Download references

Author information

Rights and permissions

Reprints and Permissions

About this article

Cite this article

MATHEWS, M. Isomeric Chondroitin Sulphates. Nature 181, 421–422 (1958) doi:10.1038/181421a0

Download citation

Further reading

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.