Reversibility of the Inactivation of Rous Sarcoma Extracts by Detergents

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Abstract

THE infectivity of an aqueous extract from a Rous sarcoma is lost if cetyl trimethyl ammonium bromide (‘Cetavlon’), a cationic detergent, is added to the active extract1. By further addition of an acid colloid substance, like ribonucleic acid2 or heparin, to the non-infective system infectivity is restored.

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References

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GUERRITORE, D. Reversibility of the Inactivation of Rous Sarcoma Extracts by Detergents. Nature 181, 419 (1958) doi:10.1038/181419a0

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